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CBDA vs. CBD – What is the difference and what are the potential health benefits?

CBDA vs. CBD – What is the difference and what are the potential health benefits?

Today we're going to dive into a fascinating topic : CBDA, also known as cannabidiolic acid. This compound from the cannabis plant has attracted particular attention, and rightly so. We're going to explore what CBDA really is and why it's worth knowing about.

You may have heard of CBD (cannabidiol) before, but CBDA is a bit of the underrated sibling. How is it different from CBD, and why should you learn about it? Let's explore this intriguing world of CBDA together and find out why it's worth looking into. So take a moment to relax and let’s unravel the mysteries of CBDA.

What are the cannabinoids in cannabis?

Cannabinoids are a group of active chemical compounds found naturally in cannabis and hemp plants. They are known for their affinities with the endocannabinoid system both in the human body and in that of other mammals. This system plays a crucial role in regulating various bodily functions, including pain, mood, the immune system, appetite and sleep.

hemp cannabinoid benefits

In total, more than 100 different cannabinoids have been identified in cannabis, the best known and most studied being:

  • Tetrahydrocannabinol (THC): This compound found in cannabis is known for its psychoactive effects, causing the feeling of "stone" often associated with the consumption of marijuana, commonly known as weed.
  • Cannabidiol (CBD): The non-psychoactive cannabinoid, has attracted much attention due to its potential therapeutic benefits, such as pain relief, anxiety reduction and anti-inflammatory properties.

Other lesser-known cannabinoids include cannabigerol (CBG), cannabinol (CBN), cannabidivarin (CBDV), and cannabigerovivarin (CBGV), to name a few. Each of these compounds has the potential to produce different effects and may contribute to the broader health benefits of cannabis.

Cannabinoids in the hemp plant

Cannabinoids can also be isolated and extracted from cannabis and hemp plants for use in medicines, dietary supplements and other products. Research into these compounds and their potential applications in healthcare continues to evolve and expand.

What is CBDA, cannabidiolic acid?


CBDA, short for cannabidiolic acid, is one of many natural compounds found in the cannabis plant, also known as the hemp plant. In fact, it's the precursor to CBD (cannabidiol), which you've probably already heard of.

CBDA is the raw form of CBD and is actually the most common form of cannabinoids found in fresh hemp plants. It exists as an acid and only transforms into CBD when heated, whether by sunlight or in a process called decarboxylation. This means that if you consume fresh cannabis, you are actually getting CBDA instead of CBD. Many cannabinoids start out as acids; for example, THC begins as THCA, and CBG comes from CBGA.

Although CBDA is less well-known than CBD, it is slowly gaining popularity due to its potential health benefits. So, let's take a closer look at why CBDA deserves special attention and what interesting properties it holds for us.

What are the potential health benefits of using CBDA oil?

Let's take a look at the potential health benefits of CBDA:

  1. Anti-inflammatory properties: It shows promise as an anti-inflammatory substance. This may be beneficial for people suffering from conditions with chronic inflammation, such as arthritis.
  2. Nausea and vomiting: It has been shown to be effective in reducing nausea and vomiting, especially important for people undergoing chemotherapy.
  3. Zen mode for stress and anxiety: There are indications that it may help reduce stress and anxiety. If you're feeling stressed or experiencing anxiety attacks, CBDA could help you find some inner peace.
  4. Epilepsy Management: Although more research is needed, there are positive signals that CBDA may help control seizures. This could be a promising development for people with epilepsy.

It is important to note that research into CBDA is still in its early stages, so the effects and optimal dosage have yet to be determined. If you are considering using CBDA oil for health purposes, it is prudent to discuss it with a healthcare professional, especially if you have any existing medical conditions or are taking medications.

What is the difference between CBD oil and CBDA oil?

laboratory examines cbd and cbda

Let’s talk about CBD and CBDA, two plant-based cannabinoids found in hemp plants. CBD, short for cannabidiol, is the better known of the two, mainly due to extensive research into its potential therapeutic benefits. On the other hand, CBDA, or cannabidiolic acid, is less well-known but is starting to attract attention due to its potential health benefits.

What distinguishes CBD from CBDA?

An important distinction is that CBD is more stable than CBDA . This means that CBD breaks down less quickly when exposed to light or heat. CBDA , on the other hand, is the precursor to CBD, and under the influence of UV rays and heat it transforms into CBD . This also explains why it can be difficult to find products containing CBDA.

With more advanced extraction methods , growers can harvest this delicate compound from fresh cannabis plants and process it into what we call raw or full-spectrum CBDa products.

The fascinating thing about cannabinoids is that they affect different people in different ways, depending on individual factors such as their chemical composition and lifestyle. This is why some people find they get better results with CBDA products, rather than CBD (CBD oil made from CBD isolate), depending on their personal wellness goals.

Comparison of Full Spectrum CBD Oil and Isolate Based CBD Oil

CBDa in full spectrum CBD oil?

Let's take a closer look at the relationship between CBDA and full-spectrum CBD oil. When you pick up a bottle of full-spectrum CBD oil and look at the ingredient list, you'll probably notice that it not only contains CBD, but also CBDA. It is not a coincidence ; the oil is made from a natural CBD extract, not a CBD isolate. In the case of CBD isolate, the oil contains only CBD.

cbd full spectrum vs cbd isolate

Full-spectrum CBDa oil is produced by extracting the entire hemp plant, which means that in addition to CBD, other cannabinoids, terpenes and flavonoids are also present in the final product. This includes CBDA, as it is one of the compounds naturally found in the hemp plant.

The process of creating full-spectrum CBD oil involves the careful extraction of cannabinoids and other beneficial compounds from the plant material. This can be done by methods such as CO2 extraction which is safer than solvent extraction. Once extraction is complete, the resulting oil is then refined and packaged for use.

The inclusion of CBDA in full-spectrum CBD oil is believed to improve the overall effectiveness of the product. This is because CBDa has its own unique properties and potential health benefits that work synergistically with CBD and other cannabinoids present. This phenomenon is often called the entourage effect , where the combination of multiple compounds enhances their individual effects.

entourage effect on cbd full spectrum

Can CBDa oil get you stoned like THC?

A common concern when it comes to cannabinoids is whether they can cause psychoactive effects. In the case of CBDA, it does not produce any intoxicating or psychoactive effects.

Unlike THC, which is responsible for the psychoactive effects of marijuana, CBDA does not bind strongly to cannabinoid receptors in the brain. This means that consuming CBDA oil or any product containing CBDA will not cause euphoria.

Instead, CBDA is known for its potential therapeutic benefits without the mind-altering effects. It can be used as a natural supplement to support overall well-being without the risks associated with THC.

How much should you take to feel the effects of CBDA oil?

Determining the appropriate dosage of CBDa oil can be difficult, as research on CBDa is still in its early stages. Additionally, factors such as individual body chemistry, weight, and the specific health condition targeted may influence optimal dosage.

It is generally recommended to start with a low dose and gradually increase until the desired effects are achieved. This allows for personal experimentation to find the dosage that suits you.

Consulting a healthcare professional experienced in cannabinoid therapy can provide valuable advice and help tailor the dosage to your specific needs. They can take your individual situation into account and provide personalized recommendations for the best results.

What are CBDA flowers?

cbda flowers

CBDA flowers are the flowers of the hemp plant that naturally contain CBDA in its raw form. These flowers are harvested from hemp plants specially grown for their high CBDA content.

Just like CBD flowers, CBDA flowers can be used for a variety of purposes, including extracting CBDA oil or other products. Some individuals also choose to use CBDA flowers to smoke or vaporize , as they can produce a more immediate effect compared to other methods of consumption.

What is CBDA flower used for (applications)?

Some common applications of CBDA flower include:

  • Pain relief: CBDA has shown promising potential as an analgesic, making it a popular choice for the management of pain and inflammation.
  • Reduction of anxiety and stress: Some individuals report that CBDA flowers promote relaxation and reduce feelings of anxiety and stress.
  • Nausea and vomiting: CBDA has been studied for its antiemetic properties, making it a potential option for people suffering from nausea and vomiting.
  • Epilepsy Management: Although more research is needed, there are indications that CBDA may have anticonvulsant properties, which could be beneficial for people with epilepsy.

It is important to note that the use of CBDA flowers and their potential health benefits are still being researched, and individual experiences may vary.


CBDa, or cannabidiolic acid, is a compound found in the cannabis plant that offers significant potential for health benefits. As a precursor to CBD, CBDA offers unique properties and may have a range of therapeutic applications.

Although research on CBDA is still in its early stages, preliminary studies suggest that it may have anti-inflammatory, anti-nausea, and anti-anxiety properties. It may also have benefits for people with epilepsy.

When it comes to choosing between CBD oil and CBDA oil, it ultimately comes down to individual preferences and desired results. CBD and CBDA each have their merits and can be used to support overall well-being. Full-spectrum CBD oil, which contains both CBD and CBDA, offers the benefits of multiple cannabinoids working together synergistically.

As always, it is important to consult a healthcare professional before starting any new supplement or treatment, including CBDA oil or CBDA flowers. They can provide personalized advice and ensure it fits your specific health needs.


Q: Is CBDA legal?
A: CBDA is legal in most countries, including the United States, as long as it is derived from hemp plants containing less than 0.3% THC. However, it is essential to check local regulations before purchasing or using CBDA products.

Q: Are there any side effects of using CBDA oil?
A: Although CBDA is generally well tolerated, some people may experience mild side effects such as dry mouth, drowsiness, or changes in appetite. It is always advisable to start with a low dose and monitor your body's response.

Q: Can CBDA be used for pets?
A: CBDA may have potential benefits for pets, just like CBD. However, it is crucial to consult a veterinarian experienced in cannabinoid therapy to ensure safety and proper dosage for your four-legged friends.

Q: Can CBDA be used topically?
A: Yes, CBDA can be used topically in the form of creams or lotions. It can offer localized relief for conditions such as inflammation, muscle soreness, or skin irritation.

Q: Can CBDA interact with medications?
A: CBDA may interact with certain medications, particularly those metabolized by the liver. It is essential to consult a healthcare professional if you are taking any medications to ensure there are no potential interactions.

Q: Can CBDA be used during pregnancy or breastfeeding?
A: It is recommended to avoid the use of CBDA or any cannabis-derived products during pregnancy or breastfeeding due to limited research on its safety in these situations.

Q: Can CBDA be detected in drug tests?
A: Although drug tests primarily target THC, it is possible that some tests detect the presence of other cannabinoids, including CBDA. If you're worried about a drug test, consider using CBD isolate products instead.

Q: Can CBDA be used for sleep disorders?
A: CBDA has not been widely studied for its potential effects on sleep disorders. However, some people report improved sleep quality and relaxation with the use of CBDA or CBD products.

Q: Is CBDA psychoactive?
A: No, CBDA is not psychoactive and does not produce the euphoric effects associated with THC. It can provide therapeutic benefits without altering the person's mental state.

Q: Can CBDA be used to treat depression?
A: There is limited research on the use of CBDA for depression. If you are suffering from depression, it is recommended that you consult a healthcare professional to discuss appropriate treatment options.


National Library of Medicine - 2020 - Cannabidiolic Acid, a Still Overlooked Bioactive Compound: An Introductory Review and Preliminary Research - 2020 - CBDA— The Raw Story - 2021 - CBD & Its Entourage

Medical Jane - Cannabinoids 101

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