As our knowledge of cannabinoids increases, our understanding of cannabis also increases. Other less known cannabinoids, such as the Cbg, already draws the attention of scientists and consumers.
According to studies preclinical, CBG and CBD could have many properties therapeutics. CBG and CBD are cannabinoids non -psychoactive which can have antioxidant, neuroprotective and analgesic activities.
In combination, CBD and CBG can provide powerful advantages anti-inflammatory for the treatment of neuroinflammation
But where do their similarities stop? The CBG differs from CBD in several ways, as revealed by a more in -depth examination. But how?
What is the CBG?
CBG is the abbreviation of Cannabigérol. THE cannabigérol is one of the more than 120 cannabinoids found in cannabis and was isolated for the first time in 1964.
CBG research is still at the preclinical stage, but available studies show that it has an important therapeutic promise.
The properties analgesics of CBG can surpass those of THC Without reaching an intoxicating effect. There is also evidence that the CBG can offer properties anticancer, antidepressive and antibacterial.
Cannabigerolic acid (CBGA) is the precursor of Thc, CBD, CBC cannabinoids. As the cannabis plant ripens and grows, the enzymes convert the CBGA into the three main cannabinoid acids: tetrahydrocannolic acid (THCA), cannabidiol acid (CBDA) and cannabichromonic acid (CBCA).
Thanks to the decarboxylation, the CBGA is converted to CBG, which allows the cannabinoid to interact with the cannabinoid receptors of the body. Research shows that the CBG has a Partial affinity for CB1 and CB2 receivers. CBG can also stimulate receptors that affect the pain, inflammation and heat sensitivity.
The CBG is generally present at low concentrations in most cannabis plants; However, selection efforts led to the creation of cannabis varieties rich in CBG. CBG predominance plants are known as CAnnabis of "Type IV".
Although these predominantly cannabigérol plants are not yet widespread in the consumer markets of hemp and cannabis, they are actively cultivated on a relatively large scale. Higher CBG levels will allow cannabinoid extraction for therapeutic purposes.
What is CBD?
CBD is the abbreviation of cannabidiol, a cannabinoid present in high concentrations in cannabis and hemp plants of type II (predominance of THC/CBD) and type III (predominance of CBD).
The CBD was first isolated from cannabis in the late 1930s, then neglected until the 1970s, when scientists were interested in its properties anticonvulsants.
Since then, research has confirmed that purified CBD has been an effective treatment for severe forms of infantile epilepsy. CBD can also have properties anti-inflammatory, analgesic, anti-anxiety, anti-nausea And sedative.
In recent years, the CBD has gained popularity due to the many therapeutic advantages it provides. CBD can help alleviate some of the undesirable side effects of THC, such as anxiety, paranoia and alteration of cognitive functions.
The CBD in combination with THC seems to offer more important therapeutic advantages than one or the other of cannabinoids alone, a phenomenon known as "entourage effect".
The CBD acts on the Endocannabinoid system by a variety of physiological paths. It has a partial affinity for CB1 and CB2 receptors, but also links to several other receptors of the endocannabinoid system. Its action mechanisms on the body are not yet sufficiently known.
What is the difference between CBG and CBD?
When consumed, CBG interacts with the human endocannabinoid system. This system consists of cannabinoid receivers (CB1 and CB2), enzymes andendocannabinoids (cannabinoids in the body).
This system is essential to maintain optimal body function, that is to say for homeostasis. The CBG links to CB1 and CB2 receptors and exercises its inhibitory properties to stimulate a number of therapeutic uses on the user.
Structure of molecules:
The molecular structures of cannabigérol and cannabidiol differ. The number and arrangement of hydrogen, carbon and oxygen atoms that make up a cannabinoid is called its molecular structure.
The CBD and the CBG have different three -dimensional forms due to their dissimilar molecular structures and are therefore binding differently to the cannabinoid receptors of the body and act differently on the body.
The molecular structure of the cannabinoid also affects its bioavailability and its degree of solubility in water.
Pharmacology:
CBD and CBG activate receptors in different ways. A 2011 study published in Psychopharmacology, for example, compared the effects of CBD and CBG on the 5-HT1A serotonin receiver.
THE CBD seems to exercise its anti-nausea effects by acting as an agonist (activator) of 5-HT1A receptors.
On the other hand, the Cbg acts as an antagonist of 5-HT1A receptors (blocking).
The results revealed that the CBG pre-treatment blocked the anti-ANÉME effects of the CBD, suggesting that the two cannabinoids are linked to the same receiver but have opposite effects on this receiver.
What therapeutic effects of the CBG?
Although no clinical trial has been conducted to examine the effects of the CBG in humans, a number of preclinical studies have provided a glimpse of some of the potential therapeutic CBG effects.
Although the CBG does not provide you with an intoxicating psychoactive experience, it can provide other unique therapeutic advantages which can help with the conditions listed below, although other trials on humans are necessary.
CBG His anti-bacterial powers:
According to A 2008 study The CBG is a antibiotic Effective against resistant meticillin (MRSA) golden staphylococcus. The antibacterial potential of 18 different cannabinoids, including cannabigérol, has been studied. The CBG surpasses all other cannabinoids tested and is as effective as the vancomycin, a powerful antibiotic.
Due to its ability to remove abnormal cell proliferation, CBG has anti -cancer properties. By inhibiting the formation of melanoma cells on the skin of the mice, research shows that it has anti-tumor properties
CBG anti-inflammatory properties:
In A 2013 study Led on mice with an induced inflammatory intestinal disease, researchers administered CBG and examined various parameters related to inflammation.
The results showed that the CBG increased the inflammatory response of mice by limiting the action of important inflammatory markers, such as IL-1, IL-10, Inos and Interferon-Y.
Cannabinoid also reduces the production of nitric oxide and the formation of ROS (reactive oxygen species) in the intestine. Scientists involved in the study concluded that the CBG should be seriously taken into account in human experiences.
Neuroprotection and increase in concentration
The CBG promotes clarity and concentration, which is one of the main reasons why users are looking for this cannabinoid. A 2014 study has examined the neuroprotective properties of cannabinoids, including the CBG, by administering the compounds to mice with induced Huntington disease.
The results show that the CBG has powerful neuroprotective properties that protect the nerve cells from the brain from damage. Cannabinoid also helps improve motor deficits and contributes to the toxicity of 3-nitropropionic acid by preserving striatal neurons.
Promotes intraocular health
The dry is located throughout the body, even in the eyes. He is responsible for maintaining eye health as part of homeostasis. THE glaucoma is an eye disease that causes pressure inside the eye and interferes with vision.
A 1990 study published in the National Library of Medicine concluded that the CBG has therapeutic potential to reduce the intraocular pressure associated with glaucoma.
Emotional and mental health support
CBG does in two ways. First of all, he Remove the degradation of the GABA, a neurotransmitter responsible for producing a calming and relaxing effect. Second, the CBG inhibits serotonin reuptake, a neurotransmitter who controls mood, pleasure and sleep. With increased levels of serotonin and gaba in the body, optimal stress levels are maintained.
Vital in the treatment of pain and tension
THE CBG is a powerful analgesic and muscle relaxing which helps relieve pain, muscle tension and discomfort. Pain management is the main reason why people turn to cannabis products as an alternative to addictive and potentially fatal pharmaceutical drugs. Cannabigérol is a better pain reliever than CBD and THC because of its great affinity for DHW receivers.
It helps fight cancer cells.
A 2014 study On mice with colon cancer concluded that the CBG plays an important role in reducing cancer cells and tumors, CBD + CBG and cancer find out more
Stimulation of appetite
A recent study shows that the CBG is an effective stimulant of appetite with minimal side effects. This makes it an appropriate choice for patients with HIV and those who undergo heavy treatments such as radiotherapy and chemotherapy.
Conclusion :
Cannabigérol is a promising cannabinoid that can offer a myriad of therapeutic advantages. Scientific research shows that CBG is a potentially powerful pain reliever, a muscle relaxant, a neuroprotector, an antibacterial, a mood stabilizer, a stimulant of appetite and an anti-inflammatory agent.
Its full potential remains to be discovered because most scientific research is in their infancy. As research continues, cannabinoid is guaranteed to provide many natural health benefits.
Where can I buy organic, safe and pure CBG?
At CBDTECH, we strive to create products that meet the health and well-being needs of consumers. We believe it is important to make cannabis compounds, especially cannabinoids, accessible to all those who need them.
Therefore, we choose the best suppliers to offer innovative, pure and safe medical cannabis products to allow consumers to fully benefit from the advantages of the plant.
