Cannabidiol (CBD) is a compound present in cannabis which, unlike THC, does not produce psychoactive effects. More and more scientific evidence indicates that CBD may have beneficial health effects, in particular with regard to the treatment of Parkinson's disease. Indeed, many symptoms of Parkinson's disease, such as tremors, muscle rigidity and behavioral changes, can be relieved by CBD. In addition, the CBD also seems to have neuroprotective effects, which means that it could help slow the progression of the disease.
What is Parkinson's disease?
Parkinson's disease is a disease that inevitably affects the brain. It is a degenerative neuro, which means that the disease slowly destroys, but gradually, brain cells.
Because the affected area of the brain is closely linked to the engine control, patients with Parkinson's disease often experience tremors, loss of balance, muscle stiffness, sleep problems and slow or uncontrollable movements of the limbs.
At what age can we contract Parkinson's disease?
The disease is normally observed in the elderly, the average age of diagnoses being 57 years.
The saddest on Parkinson's disease may be that it is not limited by age. Although most patients are men over the age of 50 when the first appearance of the disease is identified, the disease can affect anyone.
This is the story of a 45 -year -old man hospitalized in March 2020 for dry cough and muscle pain. A few days before, he had noticed a loss of smell (anosmia). His symptoms began six days earlier, the next day in his return from an extended weekend spent in the United States. It may have been exposed to the Sars-Cov-2 Coronavirus- Read more ...
How to diagnose Parkinson's disease?
In this article, we will examine more closely why theCBD oil For Parkinson's disease is increasingly popular.
A promising treatment option, when Parkinson's disease manifests for the first time, symptoms are easily confused with common aging signs, such as tremors.
4 precursor signs Parkinson's disease:
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Smell : 90% of people who have parkinson had a loss / reduction of smell about 1 year before the diagnosis of the disease
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Agitated night : People with restorative sleep disorder may be more likely to develop Parkinson's disease in the future
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Constipation : constipation can become a cause up to 20 years before diagnosis
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Anxiety and depression : depression which is frequent in people with Parkinson's disease can also precede any other symptom of the disease
However, as the disease progresses, the diagnosis becomes obvious. Although there is no remedy for Parkinson's disease, it has recently been discovered that CBD oil could simply have a beneficial effect for the relief and management of symptoms.
As such, the CBD can offer better quality of life to people with Parkinson's disease.
The saddest on Parkinson's disease may be that it is not limited by age. Although most patients are men over 50 when the first appearance of the disease is identified, The disease can touch anyone.
For the elderly, Parkinson's disease is the second most common neurological disease after Alzheimer's disease, but regardless of the patient's age, all people with Parkinson's disease are likely to lose their autonomy and Feel their quality of life impact.
Treatments for Parkinson's disease?
As such, it is crucial that patients find a treatment option, which can help improve their condition and slow down their progress as soon as possible.
Unfortunately, the current treatments of serious neurological diseases often involve a long series of undesirable side effects,
The role of dopamine in the parkinson
The reason why the CBD is very promising is its close link with the physiological functions of the body. People with Parkinson's disease often have physical, cognitive and psychological symptoms and as the disease progresses, the lack of engine control becomes more obvious.
This happens because 60 to 80% of neurons that produce dopamine are destroyed. Dopamine is a neurotransmitter of the human brain, responsible for the transfer of information between neurons. This function helps regulate various functions, such as engine control and emotional responses.
When the neurons that produce dopamine ceases to exist, a person with Parkinson's disease may feel muscle stiffness, reduced mobility, slower movements, weakened balance, coordination problems and tremors in the arms, legs, hands or jaw.
Unfortunately, it is not the only symptoms that occur due to low dopamine levels. People can also lose their natural facial expressions or live moments of dementia, lethargy, lack of sleep, depression, anxiety, fear or cognitive changes.
Parkinson and the role of CBD
Many patients with Parkinson's disease have shown that they will improve these symptoms using CBD oil. CBD studies for Parkinson's disease are just beginning, however research now shows that the CBD acts as an "reverse agonist" when it meets a specific protein receptor by the name of GPR6.
As such, it can help stimulate the production of essential dopamine. Thanks to this stimulation, CBD can help slow the progression of Parkinson's disease and make its symptoms easier to manage, suggesting new therapeutic use of CBD for the disease.
The fact that the CBD is a antioxidant powerful properties neuro protectors is the exact reason why it has precious potential for patients with serious neurological disorders, as proven in preclinical trials.
In addition to improving engine control, the CBD has also been promising to reduce anxiety, from the depression and pain, which are associated with the progression of Parkinson's disease and with the undesirable effects of the disease on the quality of life of people.
Frequent causes of Parkinson's developments
According to research, conditions such as anxiety and depression are frequent in patients with Parkinson's disease. About 40% develop anxiety disorders following the disease and 60% become depressed to a certain degree and severity, ranging from a light depression to states of severe and chronic despair.
It is assumed that the chemical changes in the brain due to the degenerative neuro nature of the disease are responsible for these emotional and personality changes.
Currently, medical evidence on the use and efficiency of CBD against Parkinson's disease is limited, mainly due to the illogical ban on cannabis and its derivatives.
However, the CBD was used to reduce depression and also interesting for the Restless legs syndrome For several years, whatever the underlying cause.
Thanks to personal stories and anecdotal evidence, the CBD has proven to be a natural alternative to the treatment of anxiety, thus reducing discomfort and cognitive weaknesses often felt by patients with Parkinson's disease.
And when used in the early stages of this progressive disease, theCannabis oil with CBD also shown neuro protective capacities, protecting brain neurons from other damage.
A good diet plays an essential role, although the CBD has shown great potential as a natural processing alternative, research on Parkinson's disease has also discovered that an unbalanced digestion can increase the risk of developing the disease of Parkinson.
This happens because some bacteria from the digestive system release toxins, which can damage mitochondria; Energy storage for cells in our body. Without a mitochondria to release energy towards the cells, they are unable to repair themselves and therefore end up dying quickly.
This digestive disruption can lead to more serious cases of Parkinson's disease
Knowing the close link between intestinal bacteria and the appearance of Parkinson's disease, good food choices can help your body stop the development of disease at an early stage.
What diet for Parkinson?
A diet rich in fermented and probiotics (lactic bacteria) can help maintain healthy mitochondria, creating a flourishing environment in the digestive tract.
This is also useful for preventing or relieving conditions such as constipation and anxiety, which are often observed in patients with Parkinson's disease.
What does studies on the symptoms of Parkinson's disease say?
According to a study, a skin disease is linked to the parkinson
Researchers started a clinical trial. It addresses a specific skin condition which affects certain patients with Parkinson's disease.
"About half of Parkinson's disease patients have a rash on the face called dermatitis Seborrheic, which looks like dandruff on the face near the nose ".
Doctors want to know if a drug containing CBD can help with a rash from Parkinson. Currently, 40 patients are registered in the first and second phases of clinical trials.
According to another study, Cannabis could be useful in Parkinson's disease
According to a survey of 1348 questionnaires sent to patients with Parkinson's disease, 8.4 % of them say they use cannabis for medical purposes.
The study was conducted by researchers from the neurology department of the Hamburg-Eppendorf university medical center in Germany. The questionnaires were distributed nationally via the Journal of members of the German Association of Parkinson's disease (1123 questionnaires) and locally in a clinic (225 questionnaires).
51 % of participants knew that cannabis could be prescribed by doctors, 28 % know the different pathways and 9 % the difference between THC and CBD.
More than 40 % of cannabis consumers have reported a reduction in pain and muscle cramps. More than 20% of the participants interviewed who consume cannabis say they have seen an improvement in the following symptoms: stiffness/Akinesia, tremors, depression, anxiety and restless legs syndrome.
And the general tolerance was good. Improving symptoms was reported by 54 % of consumers using oral and 68 % CBD who inhaled cannabis rich in THC.
Compared to the consumption of CBD, the inhalation of THC has more often been reported as reducing Akinesia and rigidity (50 % against 35 %).
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CBD could Reduce tremors chatting by Parkinson
In a controlled study on mice, a team of Danish researchers discovered that a specific synthetic cannabinoid reduced the tremor, a discovery published in the journal Nature Neuroscience and potentially revolutionary for the disease, which affects 300,000 people in France.
Researchers from the University of Copenhagen, Denmark, carried out the study and published their results in the journal Nature Neuroscience.
The essential tremor is a neurological disease that causes an involuntary rhythmic tremor.
Although they can affect any part of the body, they usually appear in the hands and are more visible when you try to perform simple tasks, as drink in a cup or tie a shoe.
Although it is not dangerous in itself, this condition worsens over time and can make the daily life of certain people extremely difficult.
The essential tremor is a disease distinct from Parkinson's disease, which also causes tremors. They generally appear for the first time in people over 40 years of age.
Summary:
Although the CBD does not offer a remedy against Parkinson's disease, this molecule can help to alleviate an improvement in the disease and strengthen the body for its fight against unwanted symptoms of Parkinson's disease.
This means that it is necessary to conduct more research and studies on humans, in order to facilitate the acceptance and availability of CBD oil for patients with Parkinson's disease.
CBD oil can help improve quality of life and gain self -esteem in Parkinson's disease, while also helping to improve their mental health by managing feelings of depression, of stress And anxiety.
