THE LSD, or DiéthylySergamide, is a psychedelic substance Powerful accidentally discovered by Swiss chemist Albert Hofmann in 1943. Although considered a dangerous and prohibited drug in high doses, a recent American study suggests that from Low doses of LSD, called "microdoses", could have beneficial effects on the brain and mood.
Points to remember:
- The study shows that the LSD has unique effects on neuronal complexity and states of consciousness compared to THC and methamphetamine.
- This increase in neural complexity with the LSD occurs in the absence of subjective modification of the state of consciousness.
- The authors suggest that the increase in the neural complexity induced by low doses of LSD, without altering the state of consciousness, could have cognitive, behavioral or therapeutic implications, and deserves more in -depth research.
Boundaries :
- The study was carried out on a small sample of participants.
- The effects of the LSD can vary depending on the dose, the individual and the context.
- Other research is necessary to confirm the results of this study.
Effects of LSD microdoses
In this study, 21 healthy adults received either a placebo or 13 or 26 micrograms of LSD, Too low doses to cause hallucinations. The researchers recorded the brain activity of the participants by electroencephalography (EEG) during the peak of drug effect.
The results have shown that a dose of 26 LSD micrograms increased on average the complexity neuronal about 12% compared to placebo. This increase in cerebral complexity is consistent with the effects of psychedelics which activate the serotonin receptors, disturbing the usual neural activity schemes.
Subjective effects of diethylysergamide microdoses
Although microdoses have not caused hallucinations, participants have reported of the changes subtle moody and awareness. Some have felt an increase in energy, good humor, elation and intellectual efficiency, as well as slight anxiety.
Therapeutic potential of LSD-25
These results suggest that microdoses LSD could have effects subtle beneficial on mood, there cognition And maybe even a therapeutic potential, Without the psychedelic effects complete. However, additional studies are necessary, especially among populations with psychiatric disorders.
In conclusion:
Although the LSD is considered an illegal and dangerous drug in high doses, this research opens the way to exploring microdoses as potential treatment for certain mental disorders, by modulating brain activity and mood in a subtle but beneficial manner .
Quotes:
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/pmc9847217/
[2] https://www.sciencedaily.com/releases/2016/04/160411153006.htm
[3] https://www.neuro-environnement.com/les-vedettes-du-mois/19-avril-1943-le-chimiste-albert-hofmann-s-offre-le-promier-trip-au-lsd -Par-Accident-APRIL-19-1943-Chemist-Albert-Hofmann-Buys-Himself-The-First-Trip-to-The-LSD-BY-ACCIDENT
[4] https://psychiatry.uchicago.edu/news/microdosing-lsd-can-it-help-or-harm-mealth-health
[5] https://fr.wikipedia.org/wiki/albert_hofmann
