CBD & CBG cannabis oil for cancer, why?

- CBDTECH FRANCE

This article is intended for those who wish to know more about the use of cannabis oil with CBD for cancer. And to understand how cannabis and CBD could potentially help certain cancer patients, it is important to understand first how cancer really develops

CBD oil for cancer?

THE cannabis has been used for centuries as natural medication by many cultures. Particularly in the east, cannabis was used as an intuitive part of medical practices with other drugs based on plants.

In Europe, our medical practices are based on clinical evidence (to prove that the drug works), which is why cannabis is not considered an accepted drug: research is still in its initial phase.

That's why he's very controversial to mention cannabis and cancer In the same sentence these days. However, this controversy does not prevent patients with cancer worldwide from consuming cannabis. They are living proof that Cannabis oil can bring a relief Indispensable to the thousands of patients diagnosed each year with cancer.

From a moral point of view, it is certainly not correct to give cancer patients false hopes on their prognosis, but at the same time, we believe that these patients should be able to choose the treatment plan they wish.

This article is intended for those who wish to know more about the use of cannabis oil with CBD for cancer. And to understand how cannabis and CBD could potentially help certain cancer patients, it is important to understand first how cancer really develops.

What is cancer?

Cancer is a body cell disease. The disease can occur at any time of life and in any part of the body, but Some factors can make cells more sensitive to cancer:

poor diet
Sedentary & stressful lifestyle choices
Also hereditary factors 5 to 10 % of cases are among the causes of cancer.

The state, cause and prognosis of cancer can vary considerably from patient to patient, but in general, cancer is due to damaged genetic equipment.

Genetic material (our DNA) is responsible for the division and replacement of body cells to ensure that a fresh supply of cells is always ready to maintain and defend the vital functions of the body. However, when our DNA is damaged, it is no longer able to create healthy cells. DNA can be damaged from birth (due to a genetic defect), or it may have been damaged due to our lifestyles.

When damaged genetic material loses control of its cellular production, the risk of unnauxed cellular growth increases. This is how tumors develop. Tumors can be benign, where normal cells divide too quickly and create relatively harmless masses; Or damaged DNA can cause abnormal cell growth that mute and become malignant tumors: cancer.

How can cannabis help?

Like the prognosis, the type and treatment of cancer can vary, the potential benefits of cannabis can differ from one person to another.

Cannabis oil with CBD Can make the difference in several ways for each patient. This was confirmed by researchers on cancer and patients, whose experiences with cannabis to fight cancer are spread over decades. Such evidence has proven that the patients can benefit from the use of cannabis oil For cancer at different stages of its progression, in particular:

- Palliative care (symptomatic treatment)
- Additional treatment
- Fight against tumors and prevention

Cannabis for palliative care

For many patients with cancer, treatment of their disease is often more exhausting than cancer itself. Radiation therapy, operations and chemotherapy are now part of the treatment methods commonly used for cancer patients. There are also many other treatment options, but the different types of cancer and treatment often cause a long series of uncomfortable symptoms, such as:

- Nausea and / or vomiting
- Pain
- Weight loss
- Wounds, edema or infections
- Lack of appetite
- Insomnia and other sleep problems
- Anxiety
- depression

Since 1975, researchers have paid a lot of attention to the impact of cannabinoids on cancer cells. THE cannabinoids being mainly used in palliative care research, Scientists focused on mitigating cancer symptoms and side effects of its treatment.

Such research indicates that cannabis oil with CBD can effectively relieve Symptoms above all, but scientists also suggest that cancer patients can:

- Use CBD to reduce nausea
- Use cannabis to relieve pain
- Take advantage of the anti-inflammatory properties of CBD
- Take up the appetite with the use of cannabis
- relieve feelings of anxiety and depression using the CBD
- Use the CBD to improve their sleep quality and feel more energetic throughout the day

Cannabis oil with CBD can potentially help reduce many side effects that cancer patients may experience due to their disease and treatment. This may also help improve their quality of life , as well as their level of motivation and hope throughout their illness. But in fact, cannabis can do more than that.

Scientists have reached even more interesting results by giving patients to patients during their cancer treatment.

Cannabis as a complementary treatment option

Studies on the combination of conventional anticancer treatments with the use of cannabis oil and CBD have attracted a lot of attention in recent years, where the medical use of cannabis slowly has won the acceptance of doctors and experts medical.

Studies are mainly focused on synthetic or isolated cannabinoids, which are copies or individual compounds of the active ingredients of the cannabis plant, but the results are always very promising.

THE cannabinoids The most studied are tetrahydrocannabinol (THC) and cannabidiol (CBD) and newly CBG (Cannabigérol).

They are known for their positive effects on nausea, pain, appetite and inflammation, and other effects are currently being studied.

Preliminary studies have also shown that CBD could make chemotherapy more effective and thus increase the effectiveness of conventional cancer treatment methods.

Recent animal studies also indicate that the CBD can help reduce the survival rates of cancer cells by activating the innate anti-tumor response of the body.

Cancer cell at the moment which divides the 3D premium photo illustration

The body is indeed capable of preventing the spread of cancer cells, but an imbalance in emzymes levels can limit this capacity.

CBD can help the body restore this natural balance and help it limit the spread of cancer. Studies have, for example, showed that CBD can remove reactions that cause metasterization of breast and lung cancers.

More specifically, the CBD is able to reduce the immune function which transports cells from one body to another. This migration of immune cells aims to protect the body from infections, but when our DNA produces abnormal cells, the immune system is unable to monitor the pace; It is stressed because it cannot repair or kill cancer cells alone.

This is where the CBD capacity to reduce cell migration becomes precious, because it prevents damaged cancer cells from spreading.

And in doing so, CBD oil is also able to reduce inflammation that creates the acidic environment (low pH) where cancer cells develop.

CBD therefore has the potential to regulate and remove the immune system. This is Quite similar to the effects of chemotherapy, which also removes the immune system in order to "break it" and kill cells that our damaged immune function cannot do alone.

In this way, the CBD helps the body activate its own capacities to fight cancer. And perhaps the most significant difference between chemotherapy and CBD is that CBD causes much fewer side effects.

Unfortunately for patients with cancer in some countries, researchers are always unable to identify exactly why CBD has such an effect on cancer cells and tumor growth.

A theory is that CBD stimulates the production of reactive oxygen species (ROS), which are pure poisons for cancer cells and help kill them.

Another theory suggests that CBD, among other cannabinoids, prevents the degradation of anandamide, an endocannabinoid that can reduce tumor growth.

Endocannabinoid system and cancer

Endocannabinoids are cannabinoid type compounds that the body produces.

Body cannabinoids are called endocannabinoids Because Endo means "interior" in Greek, while cannabinoids of the plant are called phytocannabinoids (phyto means "plant" in Greek).

Body production of endocannabioids and the entire system, which also includes the immune system and the central nervous system, are jointly called the endocannabinoid system. This system consists of a bunch of receptors throughout the body, both phyto-, endo- and synthetic.

The endocannabinoid system uses these cannabinoids to regulate the body's response to the disease. This is probably the reason why a high level of endocannabinoids and hyperactive cannabinoid receptors has been observed in patients with many types of cancer. Especially in aggressive cancer types, high levels of endocannabinoids have been observed.

This indicated that endocannabinoids could be the means for the body to try to kill cancer.

When endocannabinoids are unable to prevent cancer cells from developing and spreading, it is a sign of a bodily imbalance. This can lead to a hyperactive immune system, which would also be closely linked to the occurrence of cancer due to the acid levels that inflammatory immune responses create in the body. In his attempt to heal, our body can actually get things done.

Research has shown that cannabis oil with CBD was effective as an anti-inflammatory, regulating the immune and suppressive immune system, which means that the cannabinoid could potentially Help recreate a natural and healthy body balance. As such, CBD oil could help it Endocannabinoid system to fight cancer. The two synthetics and phytocannabinoids which activate the endocannabinoid system and those who have not in several studies shown that they reduce the spread of cancer cells by preventing tumor angiogenesis (when tumors extract "roots" by creating their own blood vessels) and also stop metastases.

In addition, scientists have located an enzyme killing endocannabinoids in malignant tumors, which also indicates that cancer cells do not like endocannabinoids. And when the researchers reduced the levels of this enzyme, the tumors developed at a slower rate.

Unfortunately, not all types of cancer respond to endocannabinoids as well. The theory explaining why this is the case suggests that the types of cancer from tissues with a low activation of the endocannabinoid receptors are less sensitive to the possible carcinogenic effects of the CBD.

The anticancer properties of cannabinoids

THE Medicine researchers prefer to use synthetic cannabinoids in their studies. These cannabinoids do not come from the plant or from our own body, but are made in a laboratory. The reason for this preference is that synthetic cannabinoids are easier to copy, which is the gold standard in medical research: reproducibility. Isolated cannabinoids (derivatives of vegetable materials and laboratory treated) are also easier to study for researchers because they facilitate the elimination process (that is to say identify which cannabinoid has certain properties).

Many active scientific studies using synthetic and isolated cannabinoids have found interesting evidence of the anticancer effects of these cannabininoids.

In animal tests, mice and rats have received small doses of Isolated THC over a period of time, and the results have shown a reduction in neoplasia (the growth of tumors associated with chronic inflammation) and also an effect preventive against cancer development.

Another study studied the effects of THC when injected directly into malignant tumors. Here, the non -inhibited growth of tumors has shown signs of remission, which confirms more the theory that THC can kill cancer cells.

Unfortunately, such experimental studies are only offered to patients with terminal cancer, because the medical world remains very reluctant to use this potentially psychoactive cannabinoid. But patients included in this study have had no adverse or psychotropic effects of THC.

Most medical studies on cannabis focus on the THC cannabinoid because it was the first cannabinoid identified and isolated by scientific researchers. It is also one of the rare cannabinoids whose researchers really know how it is metabolized in the body and, more importantly, how it affects cancer.

The THC directly activates CB2 receptors in the endocannabinoid system, and that is why researchers suggest that THC can directly cause suicide of cancer cells.

Theory of THC enduring suicide of cancer cells is based on the discovery that certain types of cancer cells have CB2 receptors. As such, THC could have the potential to bind to sick cells, to stop inflammation that keep these cells alive and can force them to commit suicide. In fact, this knowledge is not new; Scientists have known this since 1998.

However, studies that use isolated or synthetic cannabinoids rarely obtain the same convincing results as those that use natural cannabis extracts in their trials.

CBD in isolated form has anti-inflammatory, antiemetic and analgesic effects, but not of the same caliber as the entirely natural extracts of CBD of the cannabis plant.

Also known as entourage, The harmony between the different cannabinoids and also the many other natural compounds of the cannabis plant (such as terpenes and flavonoids) deeply contribute to the pharmacological reactions of cannabinoids.

Unlike isolated and synthetic cannabinoids, Cannabis-based products work in synergy with endo- and phytocannabinoids To induce the death of sick cells, while healthy cells are not affected. Natural cannabinoids are also able to initiate selective cell death in membranes, where only the defective parts of a cell die (also called autophagy). Synergy between cannabinoids has shown positive results in breast and prostate cancers, as well as lung, liver, cervix and thyroid cancers.

Due to these revolutionary results, researchers on cannabis begin to agree that the synergy between phytocannabinoids is not reproducible in a synthetic version - and that it is this synergy that makes cannabis against cancer a very valid possibility. Thus, when researchers isolate cannabinoids (or replace them entirely with synthetic analogues) in the hope of identifying their anti -cancer properties,

They also lose the synergistic effect which may well be the reason why cannabis is so interesting for cancer research.

The treatment of cancer of the future

It is still too early to say if cannabinoids will be the treatment of cancer of the future. Such a declaration will require more research, evidence and medical trials to be validated. However, researchers have already confirmed the anticancer effects of cannabinoids.

Whether it is mainly the anti-inflammatory effects of CBD, the reduction properties of cancer cells in THC or the complex synergy between the many cannabinoids present in the plant that make cannabis a viable option for the future of cancer treatment are still Unknown. Research is still at the preliminary stage, and other studies and experiences are necessary to confirm if cannabis kills cancer.

CBG for cancer

The CBG is also promising as a cancer fighter. The CBG can help by blocking receptors that cause the growth of cancer cells. In a study on mice with colorectal cancer cells, the CBG was able to inhibit the growth of cancer cells, slowing the progression of the disease. In addition, certain laboratory studies have shown that CBG inhibits the growth of prostate cancer cells, while others show an inhibition of oral cancer cells. Although there are still a lot of research to do, these studies show interesting possibilities for the treatment of cancer with the CBG.

This means that there is only one way of knowing if cannabis against cancer works for you: by trying it yourself. It is a courageous decision and therefore not the one you should make alone, which is why we always recommend that you speak with your family, a friend and your general practitioner, before you start using cannabis oil for cancer .