THE Gilles de la Tourette syndrome (SGT) is a complex neuropsychiatric disorder of unknown etiology which is characterized by involuntary vocal tics. The problems of this disease vary a lot from one patient to another. Although there is no remedy for Tourette syndrome, the effects of this syndrome often set out with age.
Thc Studies to treat the SGT
An examination of the scientific literature has revealed a limited number of cases of cases and human studies specific to the use of cannabinoids for the treatment of SGT. One of the first studies documenting the effectiveness of the THC appeared in theAmerican Journal of Psychiatry in 1999.
A study Researchers from the Hanover Faculty of Medicine, Germany, the Department of Clinical Psychiatry and Psychotherapy, reported a successful treatment of Tourette syndrome with a single dose of 10 mg of Delta-9-Thc in a 25-year-old patient In an uncontrolled open clinical trial.
The researchers reported that the total tics severity score increased from 41 to 7 within two hours of cannabinoid therapy and that the improvement was observed for a total of seven hours. "Partial tests of patients in marijuana consumption have been confirmed using a viable and reliable evaluation scale," conclude the authors.
In 2002, the researchers confirmed this initial discovery in a randomized, double blind, placebo, cross -controlled and single dose trial in 12 adult patients with TS.
This study reports "a improvement significant tics and obsessive-compulsive behavior (Toc) After treatment at the Delta-9-Thc compared to placebo."
Researchers have not reported No cognitive disorder among participants after the administration of THC and also noted: "THE THC is effective and safe in the treatment of tics and OCD in the SGT".
In 2003, the researchers conducted a randomized, double -knowledge and placebo -controlled tracking test involving 24 patients who received daily doses up to 10 mg of THC for six weeks.
Researchers reported that after long -term treatment for cannabinoids, participants experienced a significant reduction in tics and have not undergone No deleterious effect on learning, recall or verbal memory. There was also a tendency to significantly improve the duration of verbal memory during and after therapy.
A review of 2003 Evidence available published in the journal Expert Opinions in Pharmacotherapy reported that in adult patients with SGT, "Therapy at the Delta-9-Thc should be attempted ... If the drugs established or not improve tics or cause significant adverse effects".
A scientific review of 2013 reached a similar conclusion: "THC is recommended by many experts for the treatment of SGT in adult patients when the first -line treatment has failed to improve tics. Therefore, in adult patients resistant to treatment, it is necessary to consider treatment with THC ".
A study in the case of 2016 reported that the biquotidian administration of cannabinoid extracts in a patient with SGT resistant treatment was associated with an 85% reduction in the subject's motor tics and a 90% reduction in vocal tics. The authors deduced: "Our results confirm the previous research suggesting that cannabinoids are a safe and effective remedies for the SGT and could be considered in the treatment of treatment."
Another one study recent case reports confirms that the daily administration of cannabis therapy "has provided a significant improvement in symptoms"In patients with treatment resistant to treatment.
In 2017, a study Researchers from the University of Toronto have retrospectively evaluated the safety and efficiency of inhaled cannabis in 19 patients with SGT. The researchers reported: "All study participants felt clinically significant relief of symptoms, In particular a reduction in obsessive compulsive symptoms, impulsiveness, anxiety, irritability and anger access ". Eighteen of the 19 patients presented a reduction in the severity of the tics.
THC was "generally tolerated"By subjects. The conclusion of the experts is as follows:"Overall, these study participants found significant improvements in their symptoms. This is particularly striking since almost all participants had failed at least one trial of anti -ical drugs. ... In conclusion, cannabis seems to be a promising option for the treatment of tics and associated symptoms".
While the medical cannabis becomes more and more popular in the world, more and more patients with Gilles de la Tourette syndrome turn to cannabis and signal the subjective advantages of its use.
In a study Recent on Israeli patients with SGT, most of them said they had been relieved of cannabis consumption.
recently in another study, researchers interviewed 98 patients with SGT who had previous experience with cannabis. 85% of study participants said cannabis attenuated their symptoms and 93% said it improved their quality of life.
The researchers concluded: "Our results also confirm that DMs (cannabis-based drugs) can be effective and safe in the treatment of tics and comorbidities, at least in a subset of adult patients with SGT".
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TOuts The information contained in this article is based on sources and references, and all the opinions expressed are mine. I do not give advice to anyone and although I am happy to discuss subjects, if someone has another question or concern, he should ask for advice from a competent specialist.
Sources:
https://norml.org/marijuana/library/recent-medical-marijuana-research/tourette-syndrome/
