Whether you're a total novice or a CBD connoisseur, finding your ideal dose and getting results with your CBD takes work and patience.
CBD dosage in drops?
I should let you know that we sell CBD as a dietary supplement, so CBD is not a substitute for medication.
Whether you're a total novice or a CBD connoisseur, finding your ideal dose and getting results with your CBD takes work and patience.
There are some theories about CBD dosage which is based on your body weight however there is no scientific evidence for this.
I'm just giving you some guidelines so you can get started.
your journey with CBD, you have to listen to your body and adjust accordingly.
The cbd calculator to determine the best dosage
The first thing you should look for when you have your CBD oil is to look at the Total Mg of CBD in the vial.
here are the steps to find the amount in your CBD oil
- You need to divide the total Mg of CBD in the bottle by the total drops and this will give you the amount of Mg per drop.
- Now you can calculate the amount of CBD per drop
For example: I know CBD oil 10% at around 1000mg for 10ml and
that there are about 240 drops in the bottle.
- so you divide 1000 mg by 240 drops, or 4.16 mg per drop.
Personally, I think 10mg/day is a reasonable amount to start with.
- This means that after 7 days of using your amount, you can double it. Then, after 7 days, you can double it again, if you find it necessary. This will allow you to find the ideal dosage for you.
Dosing CBD can be a challenge for new users. You can use our CBD dosage guide to determine the daily dose of CBD based on your weight (see chart below).
When using CBD for the first time, we recommend taking the lowest recommended dose and slowly increasing it over a week. It's a wise thing to do when taking a new supplement to see how it interacts with your endocannabinoid system.
The maximum is 200 mg to be taken in one day. That's what we recommend.
Dosage of CBD e liquid?
here are some additional tips for finding the right dosage of CBD:
How Much CBD Should I Take?
First of all, it's fair to say that high-quality CBD is equally priced, so you don't want to waste it by dosing too much, too little, or using it incorrectly. If you follow the step-by-step method, starting with a low dose and slowly increasing it, you will give your body the ability to alert you when you have reached your "Ideal Dosage" of CBD.
To make sure you're following the step-by-step method, take note of your daily dosage, to see the improvements it brings to your body and mind, day by day. This will not only allow your body to slowly adapt to your CBD treatment, but will help you find your perfect dosage faster, while using the correct dosage of CBD.
- ✔️ Find a CBD Product That Meets Your Needs
The effects of CBD on the body are as variable as the person taking it, so what works for one person usually doesn't work the same for another. Add to that an increasingly saturated CBD market with products of varying qualities and uses, finding the right delivery method that works for you is often a challenge.
Your best bet is to take note of the CBD products you use, and adjust your dosage to find the most effective method to get the most out of your CBD cure.
Tracking your CBD cure with a dosage diary will always take some time and effort in the beginning, but writing down your experiences will help streamline your CBD journey, while taking the guesswork out of improving your health and well-being.
Track the dosage in your day-to-day diary
Often what we really want is a little more understanding of our bodies, and one way to help us is to make sure we keep track of our CBD consumption. How you use your CBD dosage diary is up to you and your needs, however, you will find our free downloadable CBD dosage calculator with simple to use and easy to follow daily entry options.
Better use of your CBD diary
Complete your dosing diary each day. Whether you take CBD in the morning or just in the evening, or even two or three times a day, write down your CBD dose each time you take it. This will ensure that you account for every mg of CBD, which will help with your CBD dosage in the future.
Write down your symptoms
Using a pre- and post-dosing symptom scale will allow you to record your symptoms and analyze your dosage more intuitively.
Be specific about how you feel
By taking note of how your CBD is helping you with each dose, you will be able to better analyze which doses work for you and what you may need to improve. By writing down your desired and unwanted effects, you will be able to find the perfect dose for your needs.
CBD against indication ⚕️
Interactions of CBD Oil Products - The CYP450 Pathway
Research began by showing that cannabidiol (CBD) has the potential to effectively help a large number of people. CBD interacts with the endocannabinoid system in a way that produces very few side effects.
While the majority of the vast majority of science indicates that CBD is safe to use and consume, it does have a few risks that, if not properly understood, could be dangerous.
One such risk is inhibition of the cytochrome P450 enzyme system . This fancy moniker refers to a family of liver enzymes that play a crucial role in drug metabolism .
This means that while itself being metabolized by the P450, CBD largely “gets its full attention” – thus stopping its action on other substances it would normally metabolize (another potent P450 inhibitor is bergapten , commonly found in grapefruit).
Of course, it's not that simple - the course and effects of inhibiting the process will depend on the dose and form of CBD intake...and also on whether we use the isolate or the whole plant extract (Full spectrum) which is the recommended method in most cases. , due to the entourage effect. In particular, the last factor must be taken into account, bearing in mind that the majority of preclinical trials and clinical trials have been carried out on pure CBD (isolate) or on drugs based on its isolate (e.g. Sativex ).
Will CBD stop drugs from working?
Without delving into the nature of the complex CBD-cytochrome interaction, one thing is certain: above a certain threshold dose, cannabidiol will gradually slow down the metabolism of certain drugs. To complicate matters, neither the threshold dose (GW Pharmaceuticals, studies have shown no interaction below the 40 mg dose, while others already estimate the limit at 25 mg), nor whether the slowing of metabolism of the drug would weaken… or enhance their effect cannot be clearly defined!
Medical advice : you must take your dose of CBD two hours apart from a treatment you have, this will allow your medication to work
Should I stop my therapy or quit CBD?
There's no need to panic, however. You probably don't need to stop taking anything, but it's always a good idea to see a doctor. Keep calm and let us remind you of the following:
- the quoted data relates to CBD as a medicine (sativex) - i.e. in the form that it is not used in our products.
- CBD is available in Europe as CBD hemp oil - organic plant products with dietary supplement status
Interactions of CBD and certain other drugs are often linked to the impact of cannabidiol on the same diseases that the drug was prescribed to cure in the first place - reducing the dose will not necessarily change the effectiveness of the treatment, because the CBD will simply replace the drug.
So far, all scientific data indicates that CBD provides more benefits than potential harm, and the latter can be avoided with a better understanding of the mechanism of interaction.
All of the above does not change the fact that even with CBD being "just" a dietary supplement, any signs - or fears - of its potential interactions with any drug (not prescription drugs) require consultation with the doctor.
Inside we can find advice like “take a grapefruit test” – if a medicine can be taken with the fruit, CBD won't do any harm either. While there's some logic to this madness (the high amounts of bergapten in these fruits are said to interact with cytochrome P450 in the same way CBD does), it's not a good idea: medicinal-grade CBD works stronger than a bigger grapefruit, Gone are the days when doctors condemned anything to do with cannabis.
Cannabidiol in the cytochrome P-450 system
Cannabinoids can inhibit the ability of the cytochrome P450 system to metabolize certain drugs,
Interestingly, it's not just CBD that has an effect on drug metabolism. Grapefruit , watercress, St. John's wort, and goldenseal all have a similar impact in terms of CYP450 inhibition.
Drugs 💊 that interact with cannabidiol
Any drug metabolized by CYP450 enzymes could potentially interact with cannabidiol. According to the Indiana University Department of Medicine, drugs known to use the CYP450 system include:
- Steroids
- HMG CoA reductase inhibitors
- Calcium channel blockers
- Antihistamines
- Prokinetics
- HIV antivirals
- Immune Modulators
- Benzodiazepines
- Antiarrhythmics
- Antibiotics
- Anesthetics
- Antipsychotics
- Antidepressants
- Anti-epileptics
- Beta-blockers
- PPI
- NSAIDs
- Angiotension Blockers II
- Oral hypoglycemic agents
- Sulfonylureas
This list does not include all potential drugs impacted by cannabidiol. Not every drug in the categories on this list will cause an interaction. For these reasons, you should consult a healthcare professional before supplementing with CBD.
Interactions between alcohol and CBD?
The CB1 receptor is an important player in the attributes of alcohol. [ 1 ]
The combination of alcohol and CBD results in a significant drop in blood alcohol levels. [ 2 ]
CBD reduces reinforcement, motivation and relapse for alcohol. [ 3 ]
CBD protects the liver from damage caused by excessive alcohol consumption. [ 4 ]
CBD prevents alcohol-induced neurodegeneration. [ 5]
CBD ameliorates alcohol-induced fatty liver disease, metabolic dysregulation, inflammation, and neutrophil-induced damage. [ 6]
Cannabinoids affect almost all enzymes responsible for alcohol metabolism. [ 7]
CB1 (THC) receptor agonists encourage alcohol consumption, while CB1 (CBD) receptor antagonists decrease it. [ 8]
Although the pharmacokinetics of alcohol and CBD are not yet fully understood, what we do know is that CBD inhibits the CYP450 enzyme system, and this system plays an important role in alcohol metabolism.
It is important to be mindful and careful when mixing CBD and alcohol.
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327810/
[2] https://www.ncbi.nlm.nih.gov/pubmed/120541
[3] https://www.ncbi.nlm.nih.gov/pubmed/28194850
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112960/
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096899/
[6] https://www.ncbi.nlm.nih.gov/pubmed/28935932
[7] https://www.ncbi.nlm.nih.gov/pubmed/1957048
[8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701763/
Caffeine ☕ and CBD Interaction
Caffeine is the best known and most consumed psychoactive drug in the world. Who doesn't even ingest a little from time to time?
CBD is rapidly gaining traction over coffee in terms of popularity, so it makes sense that people are starting to combine the two.
It turns out that the two substances go very well together!
Caffeine is molecularly very similar to adenosine, a compound produced in our body that activates the A2a receptor. Caffeine binds to A2a receptors, inhibiting adenosine reuptake.
When adenosine binds to the A2a receptor, the result is what is commonly referred to as the “rest and digest” effect. Therefore, blocking adenosine from binding results in vasodilation, which increases clarity and alertness.
CBD is also a partial agonist of the A2a receptor; So the theory goes that by combining caffeine and CBD , adenosine is blocked in all areas, resulting not only in more stimulation, but also in reduced anxiety (due to CBD's effects on other neurotransmitter systems).
It should be noted that these effects depend on the portion of CBD ingested. High amounts of CBD are more likely to cause drowsiness and sedation.
The CBD and caffeine combined will make the boost from your morning cup of coffee last all day instead of just a few hours. On the other hand, it's easy to overdo it and end up wide-eyed ;) in bed when trying to fall asleep.
Given this information, again, it's best to be mindful and careful when mixing caffeine and CBD.
Can CBD oil be addictive?
One of the most common questions we ask ourselves is: can I get addicted to CBD oil? The answer depends on what you mean by "addicted".
When looking at the chemical impacts of CBD, the answer is no. Cannabidiol is not physically addictive in the way that opiates, cocaine, alcohol, and other drugs can be. Additionally, CBD produces no physical withdrawal symptoms when you stop using it.
In fact, CBD is currently being researched as a potential tool to minimize severe withdrawal from drugs like opiates.
But, that said, human beings can become addicted to almost anything, including exercise, music, sex, and food.
Since CBD can alter essential liver enzymes, it's essential to do your research, talk to your doctor, and figure out the best way to consume CBD for your specific situation.
Information and education will be your most powerful weapons in the future.
How to use CBD oil
When taking cannabidiol, it is important to consume only the recommended serving.
Increasing or decreasing this amount may produce the opposite of the desired effect.
Download your CBD dosage diary and start your journey.
Keep in mind that some people may metabolize cannabidiol differently due to abnormalities in the cytochrome P45O (CYP450) enzyme system. And depending on when you take your medication, you may experience an unintended increase or decrease in CBD levels in your blood.
If you think you are not metabolizing CBD as expected, ask your doctor to test your cytochrome P450 enzyme system before adjusting your dosage.
Common drugs controlled in combination with cannabis (without interaction)
- Adderall (amphetamine/dextroamphetamine)
- Alcohol (contained in alcoholic beverages) (ethanol)
- amitriptyline
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- morphine
- Norco (acetaminophen/hydrocodone)
- Paracetamol (acetaminophen)
- tramadol
- Tylenol (acetaminophen)
- Valium (diazepam)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam) Zoloft (sertraline)
- Zyrtec (cetirizine)
List of free access medicines: new update
Here is the updated list of medications for self-medication in pharmacies, published on October 29, 2020 on the ANSM website*.
The following specialties are added, and are freely available in pharmacies:
MAG 2 100 mg tablet: addition of presentation in boxes of 120 tablets,
ARNIGEL gel: addition of the 45 g tube in an alumino-plastic tube,
DENTINEA oral solution in a single-dose container.
My CBD dosage calculator to follow my treatment
We've created a detailed dosage calculator to help you understand your body and to keep you on track to finding your ideal CBD dosage.
In this diary we have put together a detailed planner to dose your CBD in the easiest way possible. You can download it to your computer or device for a digital diary, or print it out to stick in the fridge or medicine cabinet and fill it in every day for best results.
In this dosage calculator you will find a simple explanation of CBD dosage & drug interactions, so you can get the most out of your CBD product, without risking your health. Don't forget to print your dosing book double-sided to save paper and the planet!
If you need a little extra help with your diary, or how to get the most out of it, don't hesitate to contact our fantastic customer service team at contact@cbdtech.fr. Download your CBD dosage diary and start your journey.
Finally, let's remember once again: the products sold by CBDtech are safe and tested so as not to induce undesirable side effects. Our extracts only contain cannabinoids from legally grown hemp. At the same time, they are not drugs in any way, and the manufacturer does not make any health claims regarding their use.
