Psilocybin: New therapy thanks to a hyperconnected brain?

There psilocybin, the main psychoactive compound of Magic mushrooms, induces a hyperconnected brain which could explain its potential therapeutic effects.

The key points

• Fascinating link between the state of cerebral hyperconnectivity induced by psilocybin and mystical experiences and the dissolution of the ego which result from it.
• Potential therapeutic effects of psilocybin, especially in the treatment of depression, anxiety disorders and tobacco dependence.

The state of cerebral hyperconnectivity induced by psilocybin

Recent research using functional magnetic resonance imaging (IRMF) has revealed that psilocybin induces a state of hyperconnectivity in the brain. This state is characterized by an increase in connections between different brain regions, creating a more integrated and fluid neural network.

Link with the mystical experience and the dissolution of the ego

The state of cerebral hyperconnectivity induced by psilocybin seems to be linked to experiences subjective deep, such as the feeling of oceanic infinity and the dissolution of the ego. These experiences, often described as mystical Or spiritual, imply a feeling of unity with the universe, a loss of individual identity and an extended perspective on reality.

Potential therapeutic effects

This state of hyperconnectivity induced by psilocybin could promote neuronal plasticity and facilitate the restructuring of dysfunctional neural networks involved in certain mental disorders

• Depression treatment :

Depression has been associated with hyperactivity in certain cerebral circuits linked to the self and rumination. Psilocybin could help "deend up" these circuits by increasing global brain connectivity.

• Treatment of anxiety disorders :

Psilocybin has also shown promising results in the treatment of certain anxious disorders, including anxiety linked to terminal cancer. For anxiety linked to death, the unit experience with the environment induced by psilocybin could reduce the fear of the annihilation of the self.

• Help to stop smoking :

In addictive disorders, such as smoking, psilocybin could reduce the strength of memory associations between environmental signals and addictive behavior

What are the potential risks associated with the use of psilocybin

Here are the main potential risks associated with the use of psilocybin, the active compound of hallucinogenic mushrooms, according to the sources consulted:

1. Psychological risks :

• Experiences of "Bad Trips" or "Returns behind" involving anxiety, fear and disturbing hallucinations
• Potential triggering of psychotic episodes in predisposed people

2. Physical risks :

• Nausea, vomiting, headache
• Increase in heart rate and blood pressure
• Muscle spasms
• Risk of fatal poisoning if the fungi are poorly identified and poisonous

3. Legal risks :

• Psilocybin and mushrooms that contain it are illegal and controlled in France and in many countries
• Risk of arrest and legal proceedings for production, sale or possession

4. Other risks :

• Development of tolerance requiring the increase in doses to feel the effects
• Risks linked to reckless behavior under influence (driving, risky activities, etc.)

Legalization of psychedelics 

Maxime Mellina's point of view of GREA (Roman group of Studies on addictions - https://grea.ch/) for this video awareness video.

Future prospects

Although challenges remain, especially in terms of legal framework and the need for additional research, current results open the way to news approaches therapeutics promising. As our understanding of psilocybin and its effects on the brain deepens, we could attend a revolution in the treatment of certain mental disorders and addictions.

A word on Tangerine Retreat

Tangerine Retreat is the first agency to offer legal psychedelic pensions based on psilocybin (hallucinogenic mushrooms) in the Netherlands, with support in French.

These 3 -day pensions take place in a peaceful and natural residence, conducive to relaxation and introspection. The program includes ceremonies with ingestion from truffles to psilocybin, framed by facilitators experienced. A process Preparation and monitoring over one year is included to maximize the benefits of experience.

The objective is to allow participants to explore their psyche, to live experiences mystical modifying the ego, and potentially of to treat of the disorders Like depression, anxiety or addictions. However, it is not a medical therapy proper.

A process selection rigorous is applied, with About 50% of the refused applications For medical or psychological reasons. The minimum age is 25 years To prevent the risks of triggering psychoses.

Tangerine Retreat was founded in 2023 by Arnaud Beauregard, a French entrepreneur convinced of the benefits of psychedelics after having held psilocybin himself. ♥learn more♥

Faq

1. Is psilocybin legal?
No, in most countries, psilocybin is considered an illegal substance because of its psychoactive properties. However, certain exceptions exist for supervised scientific research.

2. What are the side effects of psilocybin?
The most common side effects of psilocybin include nausea, headache, perception disorders and a temporary increase in blood pressure and heart rate. Psychotic episodes can occur in predisposed people.

3. Is psilocybin addictive?
No, psilocybin does not seem to be an addictive substance. However, rapid tolerance develops, which reduces effects during repeated short -term consumption.

4. Who can benefit from psilocybin for therapeutic purposes?
People with depression resisting conventional treatments, cancer -related anxiety disorders or tobacco dependence could potentially benefit from psilocybin in a framed therapeutic framework.

5. Can psilocybin be used in self-medication?
No, the use of psilocybin outside a clinical framework supervised by qualified health professionals is not recommended due to the potential risks and the lack of control over the dose and the quality of the product.